Kinetics of Hydrocarbon Generation is widely applied in source rock evaluation. The samples of immature source rock that are collected from Oligocene Sahejie Formation Member-3 and Member-4 in Dongying Depression Basin are chosen for test and analysis. To simulate real sedimentary environment of source rocks and obtain kinetic parameters， the samples of source rocks that had been extracted with organic solvents were chosen as catalyst and methyl stearate was chosen as model compound. In addition， pH and Eh values of the source rocks were analyzed. The results indicate that the hydrocarbon generation of fatty acid ester can be catalyzed obviously by minerals and the reaction can be treated as consecutive kinetic model. The hydrolysis reaction is a first-order reaction and the hydrocarbon generation reaction is a zero-order reaction. Redox environment has a significant influence on the hydrocarbon generation of organic matter catalyzed by the same kind of source rocks. Component of minerals has an important effect on hydrocarbon generation catalyzed by different minerals.