Multiple reflection is the most common noise in marine seismic data. The existence of multiple reflection degrades the signal/noise ratio, and further impacts on the reality and reliability of seismic imaging, and definitely it will affect the dependability of seismic interpretation. Multiple suppression has been a key procedure in marine seismic data processing for a long time. The forming condition and various types of multiple reflection wave were first discussed and then the difference of multiple and primary reflection wave was stated. How to select a reasonable multiple eliminating method that is applicable to marine seismic data processing was put forward. At last, a study case of a survey, which is collected from the west part of South China Sea, indicates that a hybrid method of SRME, Radon transformation, decomposition and median filter suppressed multiples significantly.