It is inferred that Miocene carbonate reservoirs probably develop in the South Uplift in Zhujiangkou Basin according to regional paleogeography and typical seismic responses with high-amplitude and low-frequency features. In the case of no drilled well, a forward modeling is used to analyze seismic responsibility to different thickness of Miocene carbonate rock. Consequently, some key thickness points, including pinchout points, tuning points,1/2 wavelength points and more than 1/2 wavelength points, are recognized in seismic profiles. Then a thickness map of Miocene carbonate rock is compiled. On integrated analysis of the Guan′s carbonate facies model, the thickness map and the seismic reflection features, the Miocene sedimentary facies isolated carbonate platform is described. It is expected that this result will be useful to future oil exploration in the carbonate rock in this uplift.