It is very difficult to estimate hydrocarbon-generation potential comprehensively by geochemical analysis only using inadequate source rock samples, among which few distributed in sags and mostly on the structure highs in Liaodong Bay area(more than 15000 km2).We studied the Paleogene samples in sags with kinetic simulations of hydrocarbon generation. According to the geochemical analysis, 4 samples of immature source rocks with different kerogen types such asⅠ,Ⅱ1,Ⅱ2,andⅢwere selected,and a series of thermal simulations of hydrocarbon generation were conducted respectively. The activation energy distributions of different source rocks were calculated from the simulation results by parallel first-order kinetic modeling. Based on the burial history and subsurface thermal gradient at an estimated point, the activation energy values were applied in the calculation of hydrocarbon generation rates from real source rocks with correlative kerogen types, which can restore the hydrocarbon generation evolutions of different source rocks in different sags. This study provides valuable data for the oil and gas potential assessment in Liaodong Bay area.