Dolomite is the key field of deep oil and gas exploration, and dissolved vug plays an important role on the oil and gas production of dolomite reservoir. This paper aims to discuss the formation and evolution of dissolved vug and the development of high-quality reservoir based on the high-temperature and high-pressure dissolved kinetic simulation of plug-scale and crystal-scale crystalline dolomite considerably occurred in deep burial realm. Three aspects of result achieved include: (1) matrix pores in dolomite tend to transform into vug after the burial dissolution, (2) pore-throat types and abundance control the rate of burial dissolution, (3) burial dissolution starts with the dissolution of high calcium dolomite or calcite. Furthermore, it is proposed that fine to medium crystalline dolomite has better chance to develop pore and to receive stronger burial dissolution, eventually to become large scale and high quality reservoir, which is an important target of hydrocarbon exploration in deep burial realm.