The integration of source and reservoir is the characteristic that shale reservoir is different from conventional reservoir. Continental organic-rich shale system has the characteristics of frequent interbedding between shale and interlayer, various types of interlayer, various types of organic matter and stronger reservoir heterogeneity. In order to find out the source-reservoir relationship of continental shale and its genesis, taking the shale of the Jurassic Ziliujing Formation in Sichuan Basin as an example, various experimental technical means such as rock thin section identification, argon ion polishing scanning electron microscope identification, organic carbon content determination and helium porosity test are used to analyze the correlation of source (TOC)-reservoir (porosity) parameters macroscopically, and interaction among inorganic minerals, organic matter, inorganic pores and organic pores (seams) microscopically. Three macro source-reservoir coupling types are identified: source-reservoir high correlation type, source-reservoir medium correlation type and source-reservoir weak correlation type. It is proposed that the development degree of organic matter-related pores determines the contribution of source to reservoir, which is the core of source-reservoir coupling relationship. Combining macro and micro characteristics, the source-reservoir coupling development model of continental shale under the control of different lithofacies assemblages is established. It is proposed that the difference of source-reservoir coupling relationship plays an important role in controlling the enrichment degree of shale oil and gas. Pure shale type and shale intercalated thin-layer shell limestone type have good development conditions of source (high TOC, favorable organic matter type) and reservoir (there are relatively many organic matter pores), the correlation between source and reservoir is relatively high, which are the most favorable lithofacies assemblages for the enrichment of continental shale oil and gas.